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TC-PTP is required for the maintenance of MYC-driven B-cell lymphomas

We sought to determine the contributions of protein tyrosine phosphatases (PTPs) to the pathogenesis of B-cell lymphomas. We found that T-cell PTP (TC-PTP) was overexpressed in transformed B cells. We hypothesized that TC-PTP may be a tumor-promoting gene that is regulated by MYC overexpression in B...

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Autori principali: Young, Ryan M., Polsky, Avital, Refaeli, Yosef
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788975/
https://ncbi.nlm.nih.gov/pubmed/19755676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-196709
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