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PRDM9 sticks its zinc fingers into recombination hotspots and between species

Meiotic recombination events typically cluster within narrow regions of the genome termed hotspots. A series of recent papers reveals that PRDM9, a C2H2-type zinc-finger protein with histone H3 lysine 4 methyltransferase activity, plays a major role in the specification of hotspots. The zinc fingers...

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Autori principali: Sandovici, Ionel, Sapienza, Carmen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Faculty of 1000 Ltd 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950028/
https://ncbi.nlm.nih.gov/pubmed/20948797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/B2-37
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