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The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?

Since the reformulation of the amyloid cascade hypothesis to focus on oligomeric aggregates of amyloid beta as the prime toxic species causing Alzheimer's disease, many researchers refocused on detecting a specific molecular assembly of defined size thatis the main trigger of Alzheimer's d...

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書目詳細資料
Main Authors: Broersen, Kerensa, Rousseau, Frederic, Schymkowitz, Joost
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949586/
https://ncbi.nlm.nih.gov/pubmed/20642866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt36
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