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The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?

Since the reformulation of the amyloid cascade hypothesis to focus on oligomeric aggregates of amyloid beta as the prime toxic species causing Alzheimer's disease, many researchers refocused on detecting a specific molecular assembly of defined size thatis the main trigger of Alzheimer's d...

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Detalhes bibliográficos
Main Authors: Broersen, Kerensa, Rousseau, Frederic, Schymkowitz, Joost
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949586/
https://ncbi.nlm.nih.gov/pubmed/20642866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt36
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