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The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?

Since the reformulation of the amyloid cascade hypothesis to focus on oligomeric aggregates of amyloid beta as the prime toxic species causing Alzheimer's disease, many researchers refocused on detecting a specific molecular assembly of defined size thatis the main trigger of Alzheimer's d...

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Sonraí Bibleagrafaíochta
Main Authors: Broersen, Kerensa, Rousseau, Frederic, Schymkowitz, Joost
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949586/
https://ncbi.nlm.nih.gov/pubmed/20642866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/alzrt36
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