Exploiting knowledge of immune selection in HIV-1 to detect HIV-specific CD8 T-cell responses

Eitemau Tebyg

• HIV escape mutations occur preferentially at HLA-binding sites of CD8 T-cell epitopes
  gan: Bronke, Corine, et al.
  Cyhoeddwyd: (2013)
• Translation of HLA-HIV associations to the cellular level: HIV adapts to inflate CD8 T cell responses against Nef and HLA adapted variant epitopes()
  gan: Almeida, Coral-Ann M, et al.
  Cyhoeddwyd: (2011)
• Automation of the ELISpot assay for high-throughput detection of antigen-specific T-cell responses
  gan: Almeida, Coral-Ann M., et al.
  Cyhoeddwyd: (2009)
• High-avidity, high-IFNγ-producing CD8 T-cell responses following immune selection during HIV-1 infection
  gan: Keane, Niamh M., et al.
  Cyhoeddwyd: (2011)
• Evaluation of the dual IFNγ/IL-2 fluorospot-assay with flow cytometry for detection of HLA-restricted HIV-specific T-cell responses in HIV controllers
  gan: Keane N, et al.
  Cyhoeddwyd: (2012-09-01)