Accommodation of physostigmine and its analogs by acetylcholinesterase is dominated by hydrophobic interactions

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• Flexibility versus “rigidity” of the functional architecture of AChE active center
  gan: Shafferman, Avigdor, et al.
  Cyhoeddwyd: (2008)
• Aging of somanyl-acetylcholinesterase adducts: facts and models.
  gan: Shafferman, A, et al.
  Cyhoeddwyd: (1997)
• Aging of phosphylated human acetylcholinesterase: catalytic processes mediated by aromatic and polar residues of the active centre.
  gan: Shafferman, A, et al.
  Cyhoeddwyd: (1996)
• The challenge of highly pathogenic microorganisms mechanisms of virulence and novel medical countermeasures /
  gan: Shafferman, Avigdor., et al.
  Cyhoeddwyd: (2010.)
• The 'aromatic patch' of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors.
  gan: Ariel, N, et al.
  Cyhoeddwyd: (1998)