The 'aromatic patch' of three proximal residues in the human acetylcholinesterase active centre allows for versatile interaction modes with inhibitors.

Lignende værker

• Aging of phosphylated human acetylcholinesterase: catalytic processes mediated by aromatic and polar residues of the active centre.
  af: Shafferman, A, et al.
  Udgivet: (1996)
• Aging of somanyl-acetylcholinesterase adducts: facts and models.
  af: Shafferman, A, et al.
  Udgivet: (1997)
• Electrostatic attraction by surface charge does not contribute to the catalytic efficiency of acetylcholinesterase.
  af: Shafferman, A, et al.
  Udgivet: (1994)
• Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center.
  af: Shafferman, A, et al.
  Udgivet: (1992)
• Bovine acetylcholinesterase: cloning, expression and characterization.
  af: Mendelson, I, et al.
  Udgivet: (1998)