Urokinase Plasminogen Activator Impairs SNP and PGE(2) Cerebrovasodilation after Brain Injury through Activation of LRP and ERK MAPK

Pial artery dilation in response to prostaglandin (PG)E(2) and the nitric oxide (NO) releaser sodium nitroprus-side (SNP) are blunted after fluid percussion brain injury (FPI), whereas responses to papaverine are unchanged. Urokinase plasminogen activator (uPA) and ERK mitogen-activated protein kina...

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Hlavní autoři: Armstead, William M., Christine, Amy J., Higazi, Abd Al-Roof, Cines, Douglas B.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948470/
https://ncbi.nlm.nih.gov/pubmed/19061381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/neu.2008.0666
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