Inhibition of integrin α(V)β(3) prevents urokinase plasminogen activator-mediated impairment of cerebrovasodilation after cerebral hypoxia/ischemia

Cerebral hypoxia (10 min) followed immediately by ischemia (20 min) (H/I) impairs cerebrovasodilation in response to hypercapnia and hypotension in the newborn pig; exogenous urokinase plasminogen activator (uPA) potentiates this effect, whereas the blockade of endogenous uPA-mediated vasoactivity p...

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Autores principales: Kiessling, J. Willis, Cines, Douglas B., Higazi, Abd Al-Roof, Armstead, William M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2009
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660240/
https://ncbi.nlm.nih.gov/pubmed/19168722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01141.2008
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