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Impaired negative regulation of homeostatically proliferating T cells
Acute lymphopenia-induced homeostatic proliferation (HP) of T cells promotes antitumor immunity, but the mechanism is unclear. We hypothesized that this is due to a lack of inhibitory signals that allows activation of T cells with low affinity for self-antigens. Tumors resist immunity in part by exp...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948436/ https://ncbi.nlm.nih.gov/pubmed/19023118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-03-139964 |
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