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The elusive CML stem cell: does it matter and how do we eliminate it?

CML is a clonal multistep myeloproliferative disease originating from and ultimately sustained by a rare population of BCR-ABL(+) cells with multilineage stem cell properties. Imatinib, the most successful of molecular targeted therapies, has revolutionized treatment of patients with CML. Despite th...

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Bibliografski detalji
Glavni autori: Carter, Bing Z., Mak, Duncan D., Cortes, Jorge, Andreeff, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948413/
https://ncbi.nlm.nih.gov/pubmed/20875553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2010.06.006
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