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The elusive CML stem cell: does it matter and how do we eliminate it?
CML is a clonal multistep myeloproliferative disease originating from and ultimately sustained by a rare population of BCR-ABL(+) cells with multilineage stem cell properties. Imatinib, the most successful of molecular targeted therapies, has revolutionized treatment of patients with CML. Despite th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948413/ https://ncbi.nlm.nih.gov/pubmed/20875553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminhematol.2010.06.006 |
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