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Structural, NMR Spectroscopic and Computational Investigation of Hemin Loading in the Hemophore HasAp from Pseudomonas aeruginosa
When challenged by low-iron conditions several Gram-negative pathogens secrete a hemophore (HasA) to scavenge hemin from its host and deliver it to a receptor (HasR) on their outer membrane for internalization. Here we report results from studies aimed at probing the structural and dynamic processes...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2948407/ https://ncbi.nlm.nih.gov/pubmed/20572666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja103498z |
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