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The Hemophore HasA from Yersinia pestis (HasA(yp)) Coordinates Hemin with a Single Residue, Tyr75, and with Minimal Conformational Change
Hemophores from Serratia marcescens (HasA(sm)) and Pseudomonas aeruginosa (HasA(p)) bind hemin between two loops, which harbor the axial ligands H32 and Y75. Hemin binding to the Y75 loop triggers closing of the H32 loop and enables binding of H32. Because Yersinia pestis HasA (HasA(yp)) presents a...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4486319/ https://ncbi.nlm.nih.gov/pubmed/23578210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400280z |
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