Functional analysis of Lyn kinase A and B isoforms reveals redundant and distinct roles in FcεRI-dependent mast cell activation

Engagement of the high affinity receptor for IgE (FcεRI) causes its phosphorylation by Lyn kinase. Two alternatively spliced variants, Lyn A and B are expressed in mast cells and both isoforms interact with FcεRI. Unlike Lyn A, Lyn B lacks a 21 amino acid region in the NH(2)-terminal unique domain....

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Detaylı Bibliyografya
Asıl Yazarlar: Alvarez-Errico, Damiana, Yamashita, Yumi, Suzuki, Ryo, Odom, Sandra, Furumoto, Yasuko, Yamashita, Toshiyuki, Rivera, Juan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948211/
https://ncbi.nlm.nih.gov/pubmed/20308635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904064
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