Scrodentoid A Inhibits Mast Cell–Mediated Allergic Response by Blocking the Lyn–FcεRIβ Interaction

Background: Mast cells are considered an attractive therapeutic target for treating allergic diseases, and the Lyn–FcεRIβ interaction is essential for mast cell activation. This study investigated the antiallergic effect of scrodentoid A (SA) on mast cells and mast cell–mediated anaphylaxis. Methods...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Qian, Fei, Zhang, Liuqiang, Lu, Shaodong, Mao, Gaohui, Guo, Fujiang, Liu, Ping, Xu, Jinwen, Li, Yiming
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6532554/
https://ncbi.nlm.nih.gov/pubmed/31156646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01103
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