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Fine-Tuning of Mast Cell Activation by FcεRIβ Chain

Mast cells play a key role in allergic reaction and disorders through the high affinity receptor for IgE (Fc(ε)RI) which is primarily activated by IgE and antigen complex. In humans, mast cells express two types of Fc(ε)RI on the cell surface, tetrameric αβγ(2) and trimeric αγ(2), whereas in mice, t...

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Main Authors: Ra, Chisei, Nunomura, Satoshi, Okayama, Yoshimichi
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Research Foundation 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353146/
https://ncbi.nlm.nih.gov/pubmed/22623922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2012.00112
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