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BRG1 helps RNA polymerase II to overcome a nucleosomal barrier during elongation, in vivo

RNA polymerase II (RNAPII) transcribes genes in a chromatin context. We have designed a system to investigate the role of chromatin remodelling during elongation in vivo, which involves inserting a strong nucleosome-positioning sequence between a promoter and a reporter gene. Our data indicate that...

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Autors principals: Subtil-Rodríguez, Alicia, Reyes, José C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948185/
https://ncbi.nlm.nih.gov/pubmed/20829883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2010.131
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