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Cockayne syndrome B protein acts as an ATP-dependent processivity factor that helps RNA polymerase II overcome nucleosome barriers

While loss-of-function mutations in Cockayne syndrome group B protein (CSB) cause neurological diseases, this unique member of the SWI2/SNF2 family of chromatin remodelers has been broadly implicated in transcription elongation and transcription-coupled DNA damage repair, yet its mechanism remains l...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Xu, Jun, Wang, Wei, Xu, Liang, Chen, Jia-Yu, Chong, Jenny, Oh, Juntaek, Leschziner, Andres E., Fu, Xiang-Dong, Wang, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7568279/
https://ncbi.nlm.nih.gov/pubmed/32989164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013379117
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