PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

Gene rearrangement in the form of an intragenic deletion is the primary mechanism of oncogenic mutation of the epidermal growth factor receptor (EGFR) gene in gliomas. However, the incidence of platelet-derived growth factor receptor-α (PDGFRA) gene rearrangement in these tumors is unknown. We inves...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ozawa, Tatsuya, Brennan, Cameron W., Wang, Lu, Squatrito, Massimo, Sasayama, Takashi, Nakada, Mitsutoshi, Huse, Jason T., Pedraza, Alicia, Utsuki, Satoshi, Yasui, Yoshie, Tandon, Adesh, Fomchenko, Elena I., Oka, Hidehiro, Levine, Ross L., Fujii, Kiyotaka, Ladanyi, Marc, Holland, Eric C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2010
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947772/
https://ncbi.nlm.nih.gov/pubmed/20889717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1972310
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