PDGFRA gene rearrangements are frequent genetic events in PDGFRA-amplified glioblastomas

Gene rearrangement in the form of an intragenic deletion is the primary mechanism of oncogenic mutation of the epidermal growth factor receptor (EGFR) gene in gliomas. However, the incidence of platelet-derived growth factor receptor-α (PDGFRA) gene rearrangement in these tumors is unknown. We inves...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ozawa, Tatsuya, Brennan, Cameron W., Wang, Lu, Squatrito, Massimo, Sasayama, Takashi, Nakada, Mitsutoshi, Huse, Jason T., Pedraza, Alicia, Utsuki, Satoshi, Yasui, Yoshie, Tandon, Adesh, Fomchenko, Elena I., Oka, Hidehiro, Levine, Ross L., Fujii, Kiyotaka, Ladanyi, Marc, Holland, Eric C.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2010
विषय:
Research Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947772/
https://ncbi.nlm.nih.gov/pubmed/20889717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1972310
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