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Cdk Phosphorylation of a Nucleoporin Controls Localization of Active Genes through the Cell Cycle

Many inducible genes in yeast are targeted to the nuclear pore complex when active. We find that the peripheral localization of the INO1 and GAL1 genes is regulated through the cell cycle. Active INO1 and GAL1 localized at the nuclear periphery during G1, became nucleoplasmic during S-phase, and the...

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Main Authors: Garvey Brickner, Donna, Brickner, Jason H.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947477/
https://ncbi.nlm.nih.gov/pubmed/20702586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-01-0065
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