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Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs

Neurodegeneration is a hallmark of many neurological diseases, including Alzheimer's, Parkinson's and the polyglutamine diseases, which are all caused by misfolded proteins that accumulate in neuronal cells of the brain. Although apoptosis is believed to contribute to neurodegeneration in...

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Detalhes bibliográficos
Main Authors: Yang, Dongshan, Wang, Chuan-En, Zhao, Bentian, Li, Wei, Ouyang, Zhen, Liu, Zhaoming, Yang, Huaqiang, Fan, Pei, O'Neill, Ashley, Gu, Weiwang, Yi, Hong, Li, Shihua, Lai, Liangxue, Li, Xiao-Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947404/
https://ncbi.nlm.nih.gov/pubmed/20660116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq313
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