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Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs

Neurodegeneration is a hallmark of many neurological diseases, including Alzheimer's, Parkinson's and the polyglutamine diseases, which are all caused by misfolded proteins that accumulate in neuronal cells of the brain. Although apoptosis is believed to contribute to neurodegeneration in...

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Autors principals: Yang, Dongshan, Wang, Chuan-En, Zhao, Bentian, Li, Wei, Ouyang, Zhen, Liu, Zhaoming, Yang, Huaqiang, Fan, Pei, O'Neill, Ashley, Gu, Weiwang, Yi, Hong, Li, Shihua, Lai, Liangxue, Li, Xiao-Jiang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947404/
https://ncbi.nlm.nih.gov/pubmed/20660116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq313
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