Species-dependent neuropathology in transgenic SOD1 pigs

Mutations in the human copper/zinc superoxide dismutase 1 (hSOD1) gene cause familial amyotrophic lateral sclerosis (ALS). It remains unknown whether large animal models of ALS mimic more pathological events seen in ALS patients via novel mechanisms. Here, we report the generation of transgenic pigs...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Yang, Huaqiang, Wang, Guohao, Sun, Haitao, Shu, Runzhe, Liu, Tao, Wang, Chuan-En, Liu, Zhaoming, Zhao, Yu, Zhao, Bentian, Ouyang, Zhen, Yang, Dongshan, Huang, Jiao, Zhou, Yueling, Li, Shihua, Jiang, Xiaodan, Xiao, Zhicheng, Li, Xiao-Jiang, Lai, Liangxue
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975503/
https://ncbi.nlm.nih.gov/pubmed/24577199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.25
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi