The Role of Vascular Endothelial Growth Factor-Induced Activation of NADPH Oxidase in Choroidal Endothelial Cells and Choroidal Neovascularization

Rac1, a subunit of NADPH oxidase, plays an important role in directed endothelial cell motility. We reported previously that Rac1 activation was necessary for choroidal endothelial cell migration across the retinal pigment epithelium, a critical step in the development of vision-threatening neovascu...

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Hauptverfasser: Monaghan-Benson, Elizabeth, Hartmann, John, Vendrov, Aleksandr E., Budd, Steve, Byfield, Grace, Parker, Augustus, Ahmad, Faisal, Huang, Wei, Runge, Marschall, Burridge, Keith, Madamanchi, Nageswara, Hartnett, M. Elizabeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947302/
https://ncbi.nlm.nih.gov/pubmed/20802176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090878
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