NOXA1-dependent NADPH oxidase regulates redox signaling and phenotype of vascular smooth muscle cell during atherogenesis

Increased reactive oxygen species (ROS) production and inflammation are key factors in the pathogenesis of atherosclerosis. We previously reported that NOX activator 1 (NOXA1) is the critical functional homolog of p67phox for NADPH oxidase activation in mouse vascular smooth muscle cells (VSMC). Her...

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Main Authors: Aleksandr E. Vendrov, Arihiro Sumida, Chandrika Canugovi, Andrey Lozhkin, Takayuki Hayami, Nageswara R. Madamanchi, Marschall S. Runge
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2019-02-01
Serier:Redox Biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2213231718309765
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