Increased mitochondrial NADPH oxidase 4 (NOX4) expression in aging is a causative factor in aortic stiffening

Aging is characterized by increased aortic stiffness, an early, independent predictor and cause of cardiovascular disease. Oxidative stress from excess reactive oxygen species (ROS) production increases with age. Mitochondria and NADPH oxidases (NOXs) are two major sources of ROS in cardiovascular s...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Canugovi, Chandrika, Stevenson, Mark D., Vendrov, Aleksandr E., Hayami, Takayuki, Robidoux, Jacques, Xiao, Han, Zhang, You-Yi, Eitzman, Daniel T., Runge, Marschall S., Madamanchi, Nageswara R.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831838/
https://ncbi.nlm.nih.gov/pubmed/31419754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101288
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