NOX4 NADPH Oxidase-Dependent Mitochondrial Oxidative Stress in Aging-Associated Cardiovascular Disease

Aims: Increased oxidative stress and vascular inflammation are implicated in increased cardiovascular disease (CVD) incidence with age. We and others demonstrated that NOX1/2 NADPH oxidase inhibition, by genetic deletion of p47phox, in Apoe(−/−) mice decreases vascular reactive oxygen species (ROS)...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Vendrov, Aleksandr E., Vendrov, Kimberly C., Smith, Alberto, Yuan, Jinling, Sumida, Arihiro, Robidoux, Jacques, Runge, Marschall S., Madamanchi, Nageswara R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692134/
https://ncbi.nlm.nih.gov/pubmed/26054376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2014.6221
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