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The Role of Vascular Endothelial Growth Factor-Induced Activation of NADPH Oxidase in Choroidal Endothelial Cells and Choroidal Neovascularization

Rac1, a subunit of NADPH oxidase, plays an important role in directed endothelial cell motility. We reported previously that Rac1 activation was necessary for choroidal endothelial cell migration across the retinal pigment epithelium, a critical step in the development of vision-threatening neovascu...

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Autors principals: Monaghan-Benson, Elizabeth, Hartmann, John, Vendrov, Aleksandr E., Budd, Steve, Byfield, Grace, Parker, Augustus, Ahmad, Faisal, Huang, Wei, Runge, Marschall, Burridge, Keith, Madamanchi, Nageswara, Hartnett, M. Elizabeth
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947302/
https://ncbi.nlm.nih.gov/pubmed/20802176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090878
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