Site-Dependent E-Cadherin Cleavage and Nuclear Translocation in a Metastatic Colorectal Cancer Model

Metastases are frequently found during colorectal cancer diagnoses and are the main determinants of clinical outcome. The lack of reliable models of metastases has precluded their mechanistic understanding and our capacity to improve outcome. We studied the effect of E-cadherin and Snail1 expression...

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Detalhes bibliográficos
Main Authors: Céspedes, María Virtudes, Larriba, María Jesús, Pavón, Miguel Angel, Álamo, Patricia, Casanova, Isolda, Parreño, Matilde, Feliu, Anna, Sancho, Francesc Josep, Muñoz, Alberto, Mangues, Ramón
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947300/
https://ncbi.nlm.nih.gov/pubmed/20813963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100079
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