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Subcutaneous preconditioning increases invasion and metastatic dissemination in mouse colorectal cancer models

Mouse colorectal cancer (CRC) models generated by orthotopic microinjection of human CRC cell lines reproduce the pattern of lymphatic, haematological and transcoelomic spread but generate low metastatic efficiency. Our aim was to develop a new strategy that could increase the metastatic efficiency...

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Detalhes bibliográficos
Main Authors: Alamo, Patricia, Gallardo, Alberto, Pavón, Miguel A., Casanova, Isolda, Trias, Manuel, Mangues, Maria A., Vázquez, Esther, Villaverde, Antonio, Mangues, Ramon, Céspedes, Maria V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944498/
https://ncbi.nlm.nih.gov/pubmed/24487410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013995
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