Orthotopic Microinjection of Human Colon Cancer Cells in Nude Mice Induces Tumor Foci in All Clinically Relevant Metastatic Sites

Despite metastasis as an important cause of death in colorectal cancer patients, current animal models of this disease are scarcely metastatic. We evaluated whether direct orthotopic cell microinjection, between the mucosa and the muscularis layers of the cecal wall of nude mice, drives tumor foci t...

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Detalhes bibliográficos
Main Authors: Céspedes, María Virtudes, Espina, Carolina, García-Cabezas, Miguel Angel, Trias, Manuel, Boluda, Alicia, Gómez del Pulgar, María Teresa, Sancho, Francesc Josep, Nistal, Manuel, Lacal, Juan Carlos, Mangues, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2007
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1864873/
https://ncbi.nlm.nih.gov/pubmed/17322390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060773
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