Tuberin Regulates E-Cadherin Localization: Implications in Epithelial-Mesenchymal Transition

The tuberous sclerosis complex 2 (TSC2) gene encodes the protein tuberin, which functions as a key negative regulator of both mammalian target of rapamycin (mTOR) C1-dependent cell growth and proliferation. Loss-of-function mutations of TSC2 result in mTORC1 hyperactivity and predispose individuals...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Barnes, Elizabeth A., Kenerson, Heidi L., Jiang, Xiuyun, Yeung, Raymond S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2010
Gaiak:
Regular Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947273/
https://ncbi.nlm.nih.gov/pubmed/20813961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090233
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