The Loss of Tuberin Promotes Cell Invasion through the β-Catenin Pathway

Mutations in the tumor suppressor tuberin (TSC2) are a common factor in the development of lymphangioleiomyomatosis (LAM). LAM is a cystic lung disease that is characterized by the infiltration of smooth muscle–like cells into the pulmonary parenchyma. The mechanism by which the loss of tuberin prom...

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Bibliographic Details
Main Authors: Barnes, Elizabeth A., Kenerson, Heidi L., Mak, Baldwin C., Yeung, Raymond S.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2010
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970858/
https://ncbi.nlm.nih.gov/pubmed/20042714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0335OC
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