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The Loss of Tuberin Promotes Cell Invasion through the β-Catenin Pathway
Mutations in the tumor suppressor tuberin (TSC2) are a common factor in the development of lymphangioleiomyomatosis (LAM). LAM is a cystic lung disease that is characterized by the infiltration of smooth muscle–like cells into the pulmonary parenchyma. The mechanism by which the loss of tuberin prom...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Thoracic Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970858/ https://ncbi.nlm.nih.gov/pubmed/20042714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0335OC |
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