The E-Cadherin and N-Cadherin Switch in Epithelial-to-Mesenchymal Transition: Signaling, Therapeutic Implications, and Challenges

Epithelial-to-Mesenchymal Transition (EMT) has been shown to be crucial in tumorigenesis where the EMT program enhances metastasis, chemoresistance and tumor stemness. Due to its emerging role as a pivotal driver of tumorigenesis, targeting EMT is of great therapeutic interest in counteracting metas...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Loh, Chin-Yap, Chai, Jian Yi, Tang, Ting Fang, Wong, Won Fen, Sethi, Gautam, Shanmugam, Muthu Kumaraswamy, Chong, Pei Pei, Looi, Chung Yeng
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830116/
https://ncbi.nlm.nih.gov/pubmed/31547193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101118
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