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IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages
IL-10 plays a central nonredundant role in limiting inflammation in vivo. However, the mechanisms involved remain to be resolved. Using primary human macrophages, we found that IL-10 inhibits selected inflammatory genes, primarily at a level of transcription. At the TNF gene, this occurs not through...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2947066/ https://ncbi.nlm.nih.gov/pubmed/20805562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100414 |
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