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Dynamic and Transient Remodeling of the Macrophage IL-10 Promoter during Transcription

To gain insight into the molecular mechanism(s) whereby macrophages produce large amounts of IL-10, we analyzed IL-10 gene expression and temporally correlated it with modifications to chromatin associated with the IL-10 promoter. In resting cells, which make essentially no cytokines, the IL-10 prom...

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Autores principales: Zhang, Xia, Edwards, Justin P., Mosser, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643023/
https://ncbi.nlm.nih.gov/pubmed/16818788
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