Direct DNA Methylation Profiling Using Methyl Binding Domain Proteins

Methylation of DNA is responsible for gene silencing by establishing heterochromatin structure that represses transcription, and studies have shown that cytosine methylation of CpG islands in promoter regions acts as a precursor to early cancer development. The naturally occurring methyl binding dom...

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Detaylı Bibliyografya
Asıl Yazarlar: Yu, Yinni, Blair, Steve, Gillespie, David, Jensen, Randy, Myszka, David G., Badran, Ahmed H., Ghosh, Indraneel, Chagovetz, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946844/
https://ncbi.nlm.nih.gov/pubmed/20507169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac1010316
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