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Turn-on DNA Damage Sensors for the Direct Detection of 8-Oxoguanine and Photoproducts in Native DNA

The integrity of the genetic information in all living organisms is constantly threatened by a variety of endogenous and environmental insults. To counter this risk, the DNA-damage response is employed for repairing lesions and maintaining genomic integrity. However, an aberrant DNA-damage response...

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Detalhes bibliográficos
Main Authors: Furman, Jennifer L., Mok, Pui-Wing, Badran, Ahmed H., Ghosh, Indraneel
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206586/
https://ncbi.nlm.nih.gov/pubmed/21520929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1116606
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