Circadian Modulation of 8-Oxoguanine DNA Damage Repair

The DNA base excision repair pathway is the main system involved in the removal of oxidative damage to DNA such as 8-Oxoguanine (8-oxoG) primarily via the 8-Oxoguanine DNA glycosylase (OGG1). Our goal was to investigate whether the repair of 8-oxoG DNA damage follow a circadian rhythm. In a group of...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Manzella, Nicola, Bracci, Massimo, Strafella, Elisabetta, Staffolani, Sara, Ciarapica, Veronica, Copertaro, Alfredo, Rapisarda, Venerando, Ledda, Caterina, Amati, Monica, Valentino, Matteo, Tomasetti, Marco, Stevens, Richard G., Santarelli, Lory
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4559719/
https://ncbi.nlm.nih.gov/pubmed/26337123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13752
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