Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosis

Opioids have been widely applied in clinics as one of the most potent pain relievers for centuries, but their abuse has deleterious physiological effects beyond addiction. We previously reported that opioids inhibit cell growth and trigger apoptosis in lymphocytes. However, the underlying mechanism...

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Bibliographische Detailangaben
Hauptverfasser: Xie, Nanchang, Li, Hui, Wei, Dailin, LeSage, Gene, Chen, Lin, Wang, Shengjun, Zhang, Yi, Chi, Lingyi, Ferslew, Kenneth, He, Lei, Chi, Zhaofu, Yin, Deling
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946474/
https://ncbi.nlm.nih.gov/pubmed/20600172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.06.006
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