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Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosis
Opioids have been widely applied in clinics as one of the most potent pain relievers for centuries, but their abuse has deleterious physiological effects beyond addiction. We previously reported that opioids inhibit cell growth and trigger apoptosis in lymphocytes. However, the underlying mechanism...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946474/ https://ncbi.nlm.nih.gov/pubmed/20600172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.06.006 |
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