Toll-Like Receptor 9 Is Required for Opioid-Induced Microglia Apoptosis

Opioids have been widely applied in clinics as one of the most potent pain relievers for centuries, but their abuse has deleterious physiological effects beyond addiction. However, the underlying mechanism by which microglia in response to opioids remains largely unknown. Here we show that morphine...

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Detalhes bibliográficos
Main Authors: He, Lei, Li, Hui, Chen, Lin, Miao, Junying, Jiang, Yulin, Zhang, Yi, Xiao, Zuoxiang, Hanley, Gregory, Li, Yi, Zhang, Xiumei, LeSage, Gene, Peng, Ying, Yin, Deling
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084705/
https://ncbi.nlm.nih.gov/pubmed/21559519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018190
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