Toll-Like Receptor 9 Is Required for Opioid-Induced Microglia Apoptosis

Opioids have been widely applied in clinics as one of the most potent pain relievers for centuries, but their abuse has deleterious physiological effects beyond addiction. However, the underlying mechanism by which microglia in response to opioids remains largely unknown. Here we show that morphine...

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Hlavní autoři: He, Lei, Li, Hui, Chen, Lin, Miao, Junying, Jiang, Yulin, Zhang, Yi, Xiao, Zuoxiang, Hanley, Gregory, Li, Yi, Zhang, Xiumei, LeSage, Gene, Peng, Ying, Yin, Deling
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084705/
https://ncbi.nlm.nih.gov/pubmed/21559519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018190
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