Defining Hypo-Methylated Regions of Stem Cell-Specific Promoters in Human iPS Cells Derived from Extra-Embryonic Amnions and Lung Fibroblasts

BACKGROUND: Human induced pluripotent stem (iPS) cells are currently used as powerful resources in regenerative medicine. During very early developmental stages, DNA methylation decreases to an overall low level at the blastocyst stage, from which embryonic stem cells are derived.Therefore, pluripot...

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Opis bibliograficzny
Główni autorzy: Nishino, Koichiro, Toyoda, Masashi, Yamazaki-Inoue, Mayu, Makino, Hatsune, Fukawatase, Yoshihiro, Chikazawa, Emi, Takahashi, Yoriko, Miyagawa, Yoshitaka, Okita, Hajime, Kiyokawa, Nobutaka, Akutsu, Hidenori, Umezawa, Akihiro
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2010
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946409/
https://ncbi.nlm.nih.gov/pubmed/20885964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013017
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