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The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells

BACKGROUND: Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several pathological features including β-amyloid (Aβ) peptide accumulation, oxidative damage, and cell death. The causes of AD and AMD are not known but several studies suggest disturbances in cholesterol met...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Dasari, Bhanu, Prasanthi, Jaya RP, Marwarha, Gurdeep, Singh, Brij B, Ghribi, Othman
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946278/
https://ncbi.nlm.nih.gov/pubmed/20836858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2415-10-22
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