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Endoplasmic reticulum stress-induced CHOP activation mediates the down-regulation of leptin in human neuroblastoma SH-SY5Y cells treated with the oxysterol 27-hydroxycholesterol

Epidemiological studies have suggested an inverse relationship between the adipocytokine leptin and the onset of Alzheimer's disease (AD), and leptin supplementation decreases amyloid-β (Aβ) production and tau phosphorylation (p-tau), two major biochemical events that play a key role in the pat...

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Detalhes bibliográficos
Main Authors: Marwarha, Gurdeep, Dasari, Bhanu, Ghribi, Othman
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3237961/
https://ncbi.nlm.nih.gov/pubmed/21983012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.09.029
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