QR-kod

Blast cell methotrexate-polyglutamate accumulation in vivo differs by lineage, ploidy, and methotrexate dose in acute lymphoblastic leukemia.

High-dose methotrexate (HDMTX) is a component of most treatment protocols for childhood acute lymphoblastic leukemia (ALL), yet recent studies of receptor-mediated transport and saturable polyglutamylation have questioned its rationale. To investigate this in vivo, methotrexate and its active polygl...

Full beskrivning

Sparad:
I publikationen:J Clin Invest
Huvudupphov: Synold, T W, Relling, M V, Boyett, J M, Rivera, G K, Sandlund, J T, Mahmoud, H, Crist, W M, Pui, C H, Evans, W E
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Clinical Investigation 1994
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294625/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7525652/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117552
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk