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Targeting ganglioside epitope 3G11 on the surface of CD4(+) T cells suppresses EAE by altering the Treg/T(h)17 cell balance
Loss of expression of the 3G11 epitope, present on disialoceramide that is predominantly found on CD4(+) T cells, has been associated with a regulatory T cell (Treg) phenotype and tolerance induction in experimental autoimmune encephalomyelitis (EAE). Here we report that treatment with anti-3G11 mAb...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2946215/ https://ncbi.nlm.nih.gov/pubmed/20679513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxq432 |
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