Magnitude and breadth of a non-protective neutralizing antibody response in an efficacy trial of a candidate HIV-1 gp120 vaccine (AIDSVAX™ B/B)

BACKGROUND: A candidate vaccine consisting of human immunodeficiency virus type 1 (HIV-1) subunit gp120 protein (AIDSVAX™ B/B) was found previously to be non-protective despite strong antibody responses against the vaccine antigens. We assessed the magnitude and breadth of neutralizing antibody resp...

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Main Authors: Gilbert, Peter, Wang, Maggie, Wrin, Terri, Petropoulos, Chris, Gurwith, Marc, Sinangil, Faruk, D'Souza, Patricia, Rodriguez-Chavez, Isaac R., DeCamp, Allan, Giganti, Mark, Berman, Phillip W., Self, Steve G., Montefiori, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946208/
https://ncbi.nlm.nih.gov/pubmed/20608874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/654816
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